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KMID : 0361020210640120901
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Korean Journal of Otolaryngology - Head and Neck Surgery
2021 Volume.64 No. 12 p.901 ~ p.905
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Clinical Characteristics of Cervical Toxoplasma Lymphadenitis
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Lee Ha-Na
Lee Seung-Yeol
Jeong Jin-Hyeok
Ji Yong-Bae
Min Kyueng-Whan
Tae Kyung
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Abstract
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Background and Objectives : Toxoplasmosis is a disease caused by an intracellular parasite,Toxoplasma gondii. There has been only a few studies done on cervical toxoplasma lymphadenitis,and this study was performed to evaluate its clinical characteristics and outcomes.
\Subjects and Method : We retrospectively reviewed the patients diagnosed with cervicaltoxoplasma lymphadenitis from January 2010 to December 2019. We investigated clinicalpathologic findings, treatment and clinical outcomes.
Results : Enrolled in the study were 21 patients who were confirmed with typical pathologicfindings in an excisional biopsy (16/21) and core needle biopsy (5/21). Nine patients were maleand 12 patients were female, with the mean age of 46.1±13.59 (19-70). All patients complainedof neck masses and 5 (23.8%) patients showed pain or tenderness. Only one (4.8%) patient hadmild fever. Fine needle aspiration cytology was performed in 5 patients, with no resultingpathognomonic outcomes in any one of the patients. CT scan was performed in 15 patients, with8 (53.3%) patients showing multiple nodal enlargements but 7 (46.6%) patients showing a singleenlarged lymph node. The most frequently involved location was level I (53.3%), followedby level II (46.6%), level V (46.6%), level III (40.0%), and level IV (20.0%). The serologic testfor toxoplasma revealed positive IgG (100%) and IgM (85.7%). Treatments were excision only(61.9%) and excision with pharmacologic treatment using sulfonamide or pyrimethamine(38.1%). There was no case of recurrence after treatment.
Conclusion : Cervical toxoplasma lymphadenitis can be diagnosed by biopsy but needle aspirationhas little role. It shows favorable clinical outcomes after treatment.
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KEYWORD
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Lymphadenitis, Lymph node, Parasite, Toxoplasma
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